Heart-Failure

Wellbeing issues, related to Thyroid are plentiful, yet new medical theories and experiments have been exploring new threats and matters that can affect other vital organs of the body through thyroid. In such a clinical breakthrough, a team of international researchers including an India-origin has revealed that a mild disorder in the normal functionality of Thyroid can affect cardiac wellness and eventually cause heart failure.

According to the new study, conducted by a research team from University of Pennsylvania in Philadelphia, the US, people with upper levels of Under-Active Thyroid Gland or medically termed as hypothyroidism are likely to be at higher risk of severe heart failure. As highlighted by the US-based researchers, including one of Indian origin, a mild decline in thyroid function can stimulate the risks of heart failures.

A thyroid-stimulating hormone or called TSH blood test is often applied for checking thyroid gland problems. TSH forces the thyroid gland to produce two hormones – triiodothyronine (T3) and thyroxine (T4). Both T3 and T4 help in controlling the body’s metabolism and are essential for the regular development of the brain, especially during the preceding years of life.

As shown in the study, people who have higher risks of heart failure often have higher levels of the thyroid hormones like TSH and T4 as well as the lower level of T3. But those patients who have higher T4 levels are more likely to have atrial fibrillation or AFib – an asymmetrical, often fast heart rate that usually results in poor blood flow. And those who have pre-existing heart failure, advanced levels of TSH, higher free T4 and inferior T3 concentrations are each seriously linked with more severe heart failure. For the study, researchers from the University of Pennsylvania in the US included a total of 1,382 patients who earlier have diagnosed with the pre-existing susceptibility to advanced heart failure.

“Our findings indicate that those who have subclinical hypothyroidism – a gentle decline in thyroid function, are at an increased need of mechanical aid to the heart with devices, heart transplantation or even death,” said Lakshmi Kannan, the Indian-origin lead author of the study from the University of Pennsylvania in Philadelphia, US.

The complete details of the study were published at the annual summit of the Endocrine Society, ENDO 2017 in Orlando.

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