Ladies Take a Note; a typical plastic chemical can cause breast cancer, warns a new study. Endocrine-disrupting chemical – commonly found the chemical in polycarbonate hard plastics, currency bills and a number of thermal paper receipts can potentially interfere with the hormones of the body and can add on to the aggressiveness of breast cancer, revealed the new study, conducted by a team of researchers from Oakland University in Michigan.
Bisphenol S (BPS) – an alternative to the chemical bisphenol A (BPA), commonly used in the plastic industry, is likely to act like oestrogens in enlarging the risks and ferociousness of breast cancer cells. According to the National Cancer Institute, most of the breast cancer cases are responsive to oestrogens, and 55 to 65% of women who become heir to a damaging mutation in the BRCA1 gene are at higher risks of developing breast cancer.
Sumi Dinda, the principal investigator of the study and an Associate Professor at Oakland University in Michigan, said, “If a woman has a transmuted BRAC1 genetic material and utilises the products containing Bisphenol S or BPS, then she is at higher risks of developing breast cancer. Adding to the statement, Sumi Dinda added, “in spite of hopes for a safer substitute to BPA, our experiment has confirmed that BPS can show signs of similar estrogen-copying behaviour to BPA and eventually can heighten the risks of breast cancer among women.”
For the study, the research team used two commercially presented breast cancer cell lines, acquired from women with estrogen-receptor-positive breast cancer and reveal the cancer cells to altering strengths of BPS or to a dormant matter as a control. In relation to the control, after 24 hours BPS is found to intensify the protein idiom in oestrogens receptor and BRCA1, as did oestrogens. After a six-days-long treatment procedure with BPS, the researchers reportedly found the breast cancer cells in both cell lines to increase in number by 12% at the lowest dose of 4 micromolar, while at highest doses of eight micromolar, the cancer cells allegedly hiked by 60%.
The complete results of the experiment were presented at ENDO 2017, the 99th annual meeting of the Endocrine Society, going on to Orlando.